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Pennsylvania Retina Specialists physicians have served as principal investigators in many clinical trials at the national level. These trials have investigated new treatments for Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR) and many other retinal disorders. The efforts of our physicians and our patients in previous clinical trials have contributed to many of the current treatment regimens used today to treat the retinal disorders.


Active Clinical Trials:

FOVISTA – Investigate the efficacy of Fovista, an anti-platelet derived growth factor (PDGF) in combination with Avastin or Eylea for treatment of wet macular degeneration.

OHR-1601 – Investigate the efficacy of  Squalamine Lactate eye drops in the treatment of wet macular degeneration. 

Allergan SEQUOIA – Investigate the efficacy and safety of Abicipar Pegol, an inhibitor to vascular endothelial growth factor A (VEGF-A) in the treatment of wet macular degeneration

Alcon RTH258-C001 – Investigate the efficacy and safety of Brolucizumab, an inhibitor to vascular endothelial growth factor (VEGF), in the treatment of wet macular degeneration

Alimera Sciences Paladin M-01-15-004 – A phase 4 study of intraocular pressure (IOP) signals in patients treated with Iluvien (fluocinolone acetonide intravitreal implant) for diabetic macular edema.


For Completed Clinical Trials Click Here.